Coenzyme Q3, Methyltransferase (COQ3) (N-Term) Peptide
COQ3
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5514134
Quick Overview for Coenzyme Q3, Methyltransferase (COQ3) (N-Term) Peptide (ABIN5514134)
Target
COQ3
(Coenzyme Q3, Methyltransferase (COQ3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- ARLYSTSQTT VDSGEVKTFL ALAHKWWDEQ GVYAPLHSMN DLRVPFIRDN
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-COQ3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- COQ3 (Coenzyme Q3, Methyltransferase (COQ3))
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Background
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Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.
Alias Symbols: COQ3,UG0215E05,
Protein Size: 369 -
Gene ID
- 51805
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NCBI Accession
- NP_059117
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UniProt
- Q9NZJ6
Target
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